Pharmas at Cedar Brook

More Biotech News

RCN’s Problems


Contracts Awarded

Corrections or additions?

These articles were prepared for the June 6, 2001 edition of U.S.

1 Newspaper. All rights reserved.

Life in the Fast Lane: InfraStor

It sounds like an entrepreneur’s dream. Put up a

website and just weeks later the federal government comes to your

virtual door and signs a contract worth well over a million dollars.

It happened to David MacRae of InfraStor Technologies Corp. in

Montgomery Knoll.

"They approached us in March because they saw our website, and they

are back for more, so we must have done a good job," says MacRae. The

federal contract involved storing a Department of Defense website that

contains hundreds of terabytes. (A million megabytes equals one

terabyte). "We pretty much wrote the specifications, and when they put

the contract out for bids, we outbid everyone else."

The name of MacRae’s business is meant to imply "infrastructure,"

because it integrates Storage Area Networks (SAN) and connects large

data storage devices to servers and workstations. "Relatively few

organizations have focused entirely on getting storage area networks

implemented," he says. "It’s not rocket science, but it does require

special knowledge that we have assembled. We have our own integration

laboratory that allows us to model a business situation." He has

relationships with such big suppliers as Gadzoox, Brocade, and

Vixel (fibre channel switch providers), DataCore Software (storage

management software), and ADIC (tape libraries).

"Our clients are medium to large-size organizations looking for

cost-effective ways to manage storage from a central resource. We

take a consultative approach to design a storage solution, customize

it, and provide equipment, software, installation, and training."

Companies with 50 or 100 servers can find it difficult to manage

storage. The question an IT department has to answer: If you have X

number of servers and some of them run out of storage space, do you

buy more storage for each machine or have a centralized source pool

that can allocate gigabytes to each server on demand.

MacRae offers the latter solution: "Putting the storage together into

one common pool uses the capacity 50 percent more effectively, so you

don’t have to buy so much storage." Using open systems modular

hardware, he says, results in an 85 percent reduction in storage

management cost.

MacRae went to the University of Toronto, Class of 1965, and has a

doctoral degree from there as well. A chemist by training, he was a

researcher for Colgate-Palmolive and Allied Signal (now Honeywell). He

and his wife, who runs a translation business (Specan International)

from their Princeton home, have two grown sons. One

is in a PhD program at UCLA and the other, cellist Alistair MacRae,

went to Princeton University and Manhattan School of Music and made

his debut last month at Carnegie Hall. His additional talent is as

webmaster: He crafted his father’s contract-winning website.

InfraStor Technologies Corp., 69 Tamarack

Circle, Montgomery Knoll, Box 8448, Princeton 08543. David M. MacRae,

president. 609-683-8844; fax, 609-683-4906. Home page:

Top Of Page
Pharmas at Cedar Brook

A company that vows to kill pain, Purdue Pharma LP, has

leased 115,000 square feet in Cedar Brook Corporate Center, an office

and science park built by Eastern Properties on Dey Road at Route 130.

The privately held company is known for its research on the principal

cause of human suffering: chronic pain. It does small molecule and

biologics discovery research of the immunological and nervous systems.

"The new facility will be the headquarters of the discovery research

operation," says Merle Spiegel, a spokesperson for the Stamford,

Connecticut, firm. About 100 people will move into the new facility,

and it is expected to open by the end of this year. "Within the next

year or two thereafter, we expect to increase the size of the facility

to 300 people," says Spiegel, noting that Purdue is one of the fastest

growing pharmaceutical firms in the world.

Meanwhile, the contract that Purdue had to manufacture Cytogen

products at 201 College Road ends this month. Purdue Pharma LP paid $4

million for some of Cytogen’s laboratory and manufacturing facilities

early in 1999, and it signed a contract to make Cytogen’s ProstaScint

and OncoScint. Cytogen will now turn to DSM Biologics Company B.V. for

this service, and DSM will make these products at its own site. Purdue

will retain the College Road facility, says Spiegel.

Among Purdue’s products are OxyContin (oxycodone HCl) and MS Contin

(morphine sulfate) for moderate to severe pain, Uniphyl (theophylline,

anhydrous) for asthma, Chirocaine (levobupivacaine injection)

anesthetic, and the over-the-counter Senokot laxatives and Betadine


Purdue is part of an international group of associated companies in 18

countries with more than 4,000 employees. It sponsors Partners Against

Pain, which offers more than 6,000 programs annually to encourage

therapeutic alliances between patients, their families, caregivers,

and healthcare professionals.

Purdue Pharma LP, Tage Honore, vice president of

discovery research. Cedar Brook Corporate Center. 203-588-8000.

Home page:

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More Biotech News

Cytogen Corporation (CYTO), 600 College Road East,

CN 5308, Princeton 08543-5308. H. Joseph Reiser, CEO.

609-987-8200; fax, 609-750-8124. Home page:

A Duke University study released on June 5 found that Cytogen’s

prostate cancer screening method, using ProstaScint, identifies the

spread of the cancer "earlier and in more patients than with

previously available imaging methods." ProstaScint is a monoclonal

antibody-based imaging agent that can image the extent and spread of

prostate cancer.

Prostate cancer is the second leading cause of cancer death among

American men, and more than one in six men develop this cancer.

Chances of survival increase when it is detected early.

Among Cytogen’s other products for prostate and other types of cancer

are BrachySeed, Quadramet, and OncoScint. Cytogen has a pipeline of

oncology products, licensed from Memorial Sloan-Kettering Center, that

use prostate-specific membrane antigen (PSMA) technologies. It has a

subsidiary, AxCell Biosciences, that is charting protein-signaling

pathways for use in drug discovery and development.

Palatin Technologies Inc. (PTN), 103 Carnegie

Center, Suite 200, Princeton 08540. Carl Spana, CEO. 609-520-1911;

fax, 609-452-0880. Home page:

Palatin Technologies has signed a lease for 28,000

square feet, the entire building at 4C Cedar Brook Drive. The R&D firm

offers products for sexual dysfunction, appendicitis detection, and

ultrasound testing. It will consolidate

its Carnegie Center and its 15,000 square foot laboratory on May

Street in Edison.

Doug Petrozzini and Ray Sohmer of Grubb & Ellis worked with Stephen

Wills, the CFO of Palatin. The developer, Eastern Properties,

constructed this brand-new building at Cedar Brook Corporate Center.

Orchid BioSciences Inc. (ORCH), 303A College Road

East, Princeton 08543. Dale R. Pfost Ph.D, CEO. 609-750-2200; fax,

609-750-2250. Home page:

A Korea-based firm, DNA Link, will be the first Asian company to buy

Orchid’s SNPstream 25K system for high throughput genotyping. DNA Link

will use the system for industrial scale single nucleotide

polymorphism (SNP) scoring — analyzing up to 25,000 SNPs per day —

and will also use Orchid’s SNP databases.

Orchid offers production services and technologies of single

nucleotide polymorphism (SNP) scoring and genetic diversity analysis.

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RCN’s Problems

RCN Corporation (RCNC), 105 Carnegie Center, Suite

300, Princeton 08540. David C. McCourt, chairman and CEO.

609-734-3700; fax, 609-734-7551. Home page:

The beleaguered cable company, which has laid off

workers and axed plans to build a prestigious campus on the former

Union Camp site, made another cutback on May 24. It announced it would

not make its promised upgrades in Princeton Township and Borough,

among other locations. The Princetons were among the first areas to

get cable installed in the 1970s and they are still using a two-line

coaxial system. Last year RCN had promised to replace those lines with

fiber-optic cable. But in

areas of Hillsborough and Franklin, where upgrades were already well

underway, cabling will be finished by 2003. RCN’s franchise is up for

renewal at the end of next year.

In an effort to recoup some of its losses, Red Basin LLC (one of RCN’s

largest investors) will buy 7.66 million shares of common stock in a

private placement at $6.53 per share. The stock peaked at nearly $75

last year but tumbled along with other telecommunications stocks.

RCN is a national single-source facilities-based communications firm

with services — Internet service, local and long distance phone, and

cable television — to the residential market.

Top Of Page

Maximus, 50 Millstone Road, Building 300, Suite

200, Windsor Corporate Plaza, East Windsor 08520. Marion Reitz,

vice president. 609-919-2800; fax, 609-918-1524.

Maximus has moved from 15,000 square feet at Ibis Plaza on

Quakerbridge Road to 38,000 square feet, occupying the second floor

at Windsor Corporate Park, and has a new phone and fax. The health

education and enrollment HMO has 4,000 employees nationally, and about

160 people work at this location. It is based in Virginia.

National Alliance for Autism Research, 99 Wall

Street, Princeton 08540. Glenn R. Tringali, chief operations

officer. 609-430-9160; fax, 609-430-9163. Home page:

The alliance expanded in April from 1,000 feet at 414 Wall Street to

3,200 feet at 99 Wall Street and installed Glenn Tringali in May as

chief operations officer. It has eight employees at this location.

Founded in 1984 by Karen Margulis London, the alliance funds and

promotes biomedical research into autism and related developmental

disorders. Tringali is a graduate of Rutgers, Class of 1973, and has

worked for the March of Dimes and several hospital foundations and was

most recently the national director of fundraising for the Juvenile

Diabetes Foundation. "I’m here to manage the growth and anticipated

growth of the foundation, and we are establishing chapters around the

country," says Tringali.

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Contracts Awarded

Icon Genetics Inc., 1 Deer Park Drive, Princeton

Research Center, Suite C, Monmouth Junction 08852. Newell Bascomb,

president. 732-329-1600; fax, 732-329-1616. Home page:

Research on wheat and rapeseed will be funded by a fifth grant from an

agency of the German government, the Federal Ministry of Education and

Research in Berlin. Icon will use the grant’s $2.9 million to decrease

development time for these European crops by using gene recombinations

and plant hybridization techniques.

WorldWater Corp. (WWAT), 55 Route 31 South,

Pennington Business Park, Pennington 08534. Quentin T. Kelly, CEO.

609-818-0700; fax, 609-818-0720.

CEO Quentin T. Kelly will make a presentation at a conference at the

World Trade Center on Monday, June 11. The New York

Society of Security Analysts is sponsoring the Alternative Energy

Industry Conference, and Kelly will tell about the water and solar

engineering company that

makes solar pumps and solar electrical systems.

Worldwater is working with Rutgers to develop drip-irrigation systems

with its proprietary solar pumping equipment. It is a principal

supplier of renewable energy and remote water supply for emerging

nations — water management and solar energy company, designing,

developing and marketing proprietary technology.

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